Pharmaceutical company Moderna has begun a phase-3 clinical trial to evaluate an investigational vaccine known as mRNA-1273 designed to protect against Covid-19 virus.
The trial, which will be conducted at the US clinical research sites, will include 30,000 participants who do not have Covid-19.
“Results from early-stage clinical testing indicate the investigational mRNA-1273 vaccine is safe and immunogenic, supporting the initiation of Phase 3 clinical trial,” said Anthony S. Fauci from National Institute of Allergy and Infectious Diseases (NIAID) in the US.
“This scientifically rigorous, randomised, placebo-controlled trial is designed to determine if the vaccine can prevent Covid-19 and for how long such protection may last,” Fauci added.
The mRNA-1273 is designed to induce neutralising antibodies directed at a portion of the coronavirus “spike” protein, which the virus uses to bind to and enter human cells.
Moderna’s vaccine was co-developed by the Cambridge University and the NIAID, part of the National Institutes of Health (NIH).


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